CANCER THERAPY AND RISK OF CONGENITAL MALFORMATIONS IN CHILDREN FATHERED BY MEN TREATED FOR TESTICULAR GERM-CELL CANCER: A NATIONWIDE REGISTER STUDY.

Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study.

BackgroundBecause of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer.Previous register studies indicate increased CM risk among children conceived after paternal cancer but lack data on oncological treatment.Increased CM ris

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Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles

Extracellular vesicles (EVs) are involved in a wide range of physiological and pathological processes by shuttling material out of and between cells.Tissue EVs may thus lend insights into disease mechanisms and also betray disease bismarck piping tip when released into easily accessed biological fluids.Since brain-derived EVs (bdEVs) and their carg

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